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Multiple Choice

What is the recommended initial IV fluid bolus for post-arrest hypotension?

After a cardiac arrest, low blood pressure is often due to relative hypovolemia and vasodilation. The first move is to restore preload with an isotonic crystalloid bolus so the heart can pump more effectively and improve organ perfusion. An initial 1–2 liters of normal saline or lactated Ringer’s is the standard starting dose, titrated to the patient’s response and blood pressure, then reassessed quickly. Dextrose solutions are not used for initial resuscitation because they don’t reliably raise blood pressure and can lead to high blood glucose levels, which is undesirable in the acute post-arrest period. Giving a large amount of fluid all at once, such as 3–4 liters, increases the risk of fluid overload and pulmonary edema, especially if the patient has underlying heart or lung issues. While vasopressors may be needed if hypotension persists after an adequate fluid challenge, the priority is to correct potential hypovolemia first with an isotonic crystalloid bolus.

After a cardiac arrest, low blood pressure is often due to relative hypovolemia and vasodilation. The first move is to restore preload with an isotonic crystalloid bolus so the heart can pump more effectively and improve organ perfusion. An initial 1–2 liters of normal saline or lactated Ringer’s is the standard starting dose, titrated to the patient’s response and blood pressure, then reassessed quickly.

Dextrose solutions are not used for initial resuscitation because they don’t reliably raise blood pressure and can lead to high blood glucose levels, which is undesirable in the acute post-arrest period. Giving a large amount of fluid all at once, such as 3–4 liters, increases the risk of fluid overload and pulmonary edema, especially if the patient has underlying heart or lung issues. While vasopressors may be needed if hypotension persists after an adequate fluid challenge, the priority is to correct potential hypovolemia first with an isotonic crystalloid bolus.