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Multiple Choice

Which statement best describes treatment for a black widow spider bite regarding benzodiazepines?

The main idea is that black widow venom causes intense muscle cramping and neuromuscular hyperactivity, which are best treated by a medication that quiets the nervous system. A benzodiazepine does exactly that by enhancing GABA activity in the CNS, which reduces muscle tone and spasm while also helping with anxiety and agitation. In practice, this can markedly lessen the cramping and discomfort from the bite, and opioids like morphine may be used for additional pain relief if needed. Other options don’t address the underlying problem. Calcium gluconate isn’t effective against the venom’s effects on nerves and muscles. Epinephrine is reserved for allergic reactions or life-threatening anaphylaxis, not for venom-induced cramps. Simply observing the patient without addressing the cramps and pain would allow symptoms to persist or worsen.

The main idea is that black widow venom causes intense muscle cramping and neuromuscular hyperactivity, which are best treated by a medication that quiets the nervous system. A benzodiazepine does exactly that by enhancing GABA activity in the CNS, which reduces muscle tone and spasm while also helping with anxiety and agitation. In practice, this can markedly lessen the cramping and discomfort from the bite, and opioids like morphine may be used for additional pain relief if needed.

Other options don’t address the underlying problem. Calcium gluconate isn’t effective against the venom’s effects on nerves and muscles. Epinephrine is reserved for allergic reactions or life-threatening anaphylaxis, not for venom-induced cramps. Simply observing the patient without addressing the cramps and pain would allow symptoms to persist or worsen.